Cedar Girls' Secondary were second in 4:19.78 while Nanyang Girls' High finished third in 4:20.14.
The quartet of Nurul Syarah Bte Razali, Diane Pragasam, Ismi Zakiah Bte Kashful Anwar, and Raine Oh won Sports School's 11th consecutive title.
Arissa Rashid of Nanyang Girls' High was second in 2:31.89 while Levyn Wong of Dunman High School was third in 2:31.90.
Hu Huaxin of Hwa Chong Institution won silver in 4:23.36 while Shamus Lim, also of HCI, was third in 4:24.54.
Teammate Nicole Low also broke the old record with a time of 7:56.82 despite running the steeplechase event for the first time. Faye Chiang (#71, RI) finished third in 8:25.16.
Dave Tung of SJI came in second in 6:48.06 while Ruben S/O Loganathan of Guangyang was just 0.33s behind in third with a 6:48.39.
Sudarshan Udpa of SAJC bagged silver with a time of 10:46.90 while Teng Jian Ling of VJC clinched bronze in 10:47.11.
Elizabeth Liau and Caitlyn Yeo, both from CHIJ St. Nicholas Girls' School, came in second (05:36.41) and third (05:42.56) respectively.